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HydroFlow

Cartridges-Modified Polyethersulfone Filters

HydroFlow cartridge is a filter specifically designed for reduction of bioburden and particulate levels to protect final 0.1 and 0.2 um system filters. The filter medium is Accupor membrane, i.e., modified polyethersulfone hydrophilic membrane developed by Absolute Filters for various applications.

 

HydroFlow cartridge is designed for low cost, higher throughput than Nylon, PVDF, or cellulose esters membrane cartridge.

Performance Advantages

  • Constructed of only two materials, i.e., modified polyethersulfone and polypropylene with no adhesives to ensure lower extractables
  • All components meet USP Class VI-121°C Plastics Tests for biosafety, and are listed as being acceptable for food contact applications according to the Code of Federal Regulation, Title 21
  • Provides faster flow rate and higher throughput than Nylon, PVDF, or cellulose esters membrane filter
  • Reduced microbial bioburden and particulate levels to protect final filters
  • Available in various inlet/outlet configurations accordingly easy installation filtration system

Typical Applications

Pharmaceuticals and Biologicals: Parenterals, Ophthalmics, Oral and topical medicines, Serum, Tissue culture media, Wash and rinse water, Diagnostic reagents, Buffers, Vaccines, Bottle and vial washers, Dry compressed gases, Make-up water

 

Food and Beverages: Alcohols, Mineral water, DI and RO water, Dry compressed gases, Juices and other potable liquids

Bulk Chemicals: Selected acids, Diluted bases, Alcohols

Inks: Water and alcohol based inks

 

 

 

Materials of Construction

  • Filter Media: Single layer of pleated Accupor membrane, i.e., modified polyethersulfone hydrophilic membrane
  • Support Material: Polypropylene
  • Structure Components: Polypropylene
  • Sealing Technology: Thermal Bonding

Nominal Length 10, 20, 30 and 40 inch (25.4, 50.8, 76.2 and 101.6 cm)

Diameter 2.7 inches (6.9 cm)

Nominal Pore Size 0.2 um, 0.45 um and 0.8 um


Typical Effective Filtration Area

7 ft2 (0.65 m2) per 10 inch

 

Maximum Operating Temperature* 85 °C (185 °F) at 30 psi (2.1 bar)

*Supported adapters are recommended for applications at elevated temperature over 60 °C

Sterilization/Sanitization Methods

Chemical: Peracetic acid, chlorinated alkaline products, bleach, sulfur dioxide, and hydrogen peroxide at typical sanitization concentrations and temperatures

  • Hot Water: 88 °C (190 °F) at 5 psi (0.3 bar)
  • Autoclave: 121 °C (250 °F) for 30 minutes up to 6 cycles
  • In-line Steam: 140 °C (284 °F) for 60 minutes at 2 psi (0.14 bar) up to 3 cycles

Maximum Differential Forward Pressure

0.2 um and 0.45 um: 60 psi (4.1 bar) at ambient temperature

0.8 um: 50 psi (3.4 bar) at ambient temperature

Maximum Differential Back Pressure 15 psi (1.0 bar) at ambient temperature

Recommended Integrity Test

  • Minimum Bubble Point:
  • 0.2 um: 45 psi (3.1 bar) in water
  • 0.45 um: 28 psi (1.9 bar) in water
  • 0.8 um: 10 psi (0.7 bar) in water

Typical Water Flow Rate

  • 0.2 um: 3 gpm/psi/10 inch (16.5 lpm/0.1 bar/ 25.4 cm)
  • 0.45 um: 5.2 gpm/psi/10 inch (28.5 lpm/0.1 bar/25.4 cm)
  • 0.8 um: 10 gpm/psi/10 inch (54.9 lpm/0.1 bar/25.4 cm)

Oxidizable Substances Filtrate meets USP XXII requirements for purified water with

Biosafety and CFR Title 21 Materials pass USP Class VI-121° C Plastics Tests and are listed as being acceptable for food contact according to the Code of Federal Regulation, Title 21

Endotoxin Level < 0.25 EU/mL utilizing Limulus Amoebocyte Lysate (LAL) test

 

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